Findings

What do systematic reviews say?

7 questions · 7 findings · 2 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 2 · 28.6%Very low 0 · 0%Low 4 · 57.1%Moderate 1 · 14.3%High 0 · 0%

Regular formoterol and ICS vs same‐dose ICS

All‐cause mortality · children and adolescents with chronic asthma

1 finding from 1 review

Inhaled steroids with and without regular formoterol for asthma: serious adverse events 2019 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 4035 participants
Low

Regular formoterol and ICS vs same‐dose ICS

All‐cause mortality · adults, chronic asthma: all‐cause mortality

Regular formoterol and ICS showed no clear difference in all‐cause mortality compared with same‐dose ICS (moderate certainty).

1 finding from 1 review

Inhaled steroids with and without regular formoterol for asthma: serious adverse events 2019 · Cochrane Headline outcomes only
OR 1.25 [0.61, 2.56]
32 studies · 35751 participants
Moderate

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality formoterol/budesonide vs salmeterol/budesonide · adults, chronic asthma: all‐cause mortality

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 229 participants
GRADE not reported

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality ‐ formoterol and budesonide vs salmeterol and fluticasone · adults, chronic asthma: all‐cause mortality

Adults: formoterol/ICS showed no clear difference in all‐cause mortality ‐ formoterol/budesonide vs salmeterol/fluticasone compared with salmeterol/ICS (low certainty).

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
OR 1.03 [0.06, 16.44]
7 studies · 5935 participants
Low

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality ‐ formoterol/mometasone vs salmeterol/fluticasone · adults, chronic asthma: all‐cause mortality

Adults: formoterol/ICS showed no clear difference in all‐cause mortality ‐ formoterol/mometasone vs salmeterol/fluticasone compared with salmeterol/ICS (low certainty).

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
OR 4.46 [0.23, 85.4]
2 studies · 1126 participants
Low

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality ‐ formoterol/fluticasone vs salmeterol/fluticasone · adults, chronic asthma: all‐cause mortality

Adults: formoterol/ICS showed no clear difference in all‐cause mortality ‐ formoterol/fluticasone vs salmeterol/fluticasone compared with salmeterol/ICS (low certainty).

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
OR 7.39 [0.15, 372.38]
2 studies · 270 participants
Low

Adults: formoterol/ICS vs salmeterol/ICS

Mortality (all‐cause) ‐ formoterol versus salbutamol ( · adults, chronic asthma: all‐cause mortality

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1257 participants
GRADE not reported