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What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 8 findings · 2 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 6 · 75%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%

Pre‐emptive antifungal therapy vs empirical antifungal therapy

All‐cause mortality · people with cancer who have febrile neutropenia

Pre‐emptive antifungal therapy showed no clear difference in all‐cause mortality compared with empirical antifungal therapy (low certainty).

1 finding from 1 review

Aspirin vs vitamin K antagonist (VKA)

All‐cause mortality · ambulatory patients with multiple myeloma receiving immunomodulatory agents

It is very uncertain whether aspirin (ASA) changes all‐cause mortality compared with vitamin K antagonist (VKA) (very low certainty).

2 findings from 1 review

Aspirin vs low molecular weight heparin

All‐cause mortality · ambulatory patients with multiple myeloma receiving immunomodulatory agents

It is very uncertain whether aspirin (ASA) changes all‐cause mortality compared with low molecular weight heparin (LMWH) (very low certainty).

2 findings from 1 review

Vitamin K antagonists vs low molecular weight heparin

All‐cause mortality · ambulatory patients with multiple myeloma receiving immunomodulatory agents

It is very uncertain whether vitamin K antagonist (VKA) changes all‐cause mortality compared with low molecular weight heparin (LMWH) (very low certainty).

2 findings from 1 review