Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Kidney and Transplant

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

All‐cause death ( · preventing the progression of CKD

It is very uncertain whether metformin changes all‐cause death ( compared with placebo (very low certainty).

1 finding from 1 review

Metformin for preventing the progression of chronic kidney disease 2024 · Cochrane Headline outcomes only
RR 1 [0.76, 1.32]
3 studies · 865 participants
Very low

All‐cause death ( · preventing the progression of CKD

Metformin showed no clear difference in all‐cause death ( compared with active control (low certainty).

1 finding from 1 review

Metformin for preventing the progression of chronic kidney disease 2024 · Cochrane Headline outcomes only
RR 0.95 [0.63, 1.43]
3 studies · 5608 participants
Low