Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

18 questions · 18 findings · 3 reviews · Kidney and Transplant

No studies found 1 · 5.6%GRADE not reported 0 · 0%Very low 2 · 11.1%Low 13 · 72.2%Moderate 1 · 5.6%High 1 · 5.6%

Angiotensin‐converting enzyme inhibitors vs placebo or no treatment

Death (all causes) · people with diabetes and kidney disease

Angiotensin‐converting‐enzyme inhibitors showed no clear difference in all‐cause death Median compared with placebo or no treatment (low certainty).

1 finding from 1 review

Angiotensin receptor blockers (ARBs) vs angiotensin‐converting enzyme inhibitors (ACEis)

Death (all causes) · people with diabetes and kidney disease

Angiotensin receptor blockers showed no clear difference in all‐cause death Median compared with angiotensin‐converting‐enzyme inhibitors (low certainty).

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors vs ACEi plus angiotensin receptor blockers

Death (all causes) · people with diabetes and kidney disease

Angiotensin‐converting‐enzyme inhibitors (ACEi) alone showed no clear difference in all‐cause death Median compared with ACEi plus angiotensin receptor blockers (low certainty).

1 finding from 1 review

Angiotensin receptor blockers (ARB) alone vs angiotensin‐converting‐enzyme inhibitors plus ARB

Death (all causes) · people with diabetes and kidney disease

Angiotensin receptor blockers (ARB) alone showed no clear difference in all‐cause death Median compared with angiotensin‐converting‐enzyme inhibitors plus ARB (low certainty).

1 finding from 1 review

Angiotensin receptor blockers (ARBs) vs another ARB

Death (all causes) · people with diabetes and kidney disease

It is very uncertain whether angiotensin receptor blocker (ARB) changes all‐cause death Median compared with another ARB (very low certainty).

1 finding from 1 review

Angiotensin receptor blockers (ARBs) vs placebo or no treatment

Death (all causes) · people with diabetes and kidney disease

Angiotensin receptor blockers showed no clear difference in all‐cause death Median compared with placebo or no treatment (low certainty).

1 finding from 1 review