Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Kidney and Transplant

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 1 · 16.7%High 1 · 16.7%

All‐cause death · solid organ transplant recipients

Ganciclovir showed no clear difference in all‐cause death compared with aciclovir (moderate certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 1.13 [0.82, 1.58]
8 studies · 1138 participants
Moderate

All‐cause death · solid organ transplant recipients

Valaciclovir showed no clear difference in all‐cause death compared with ganciclovir or valganciclovir (low certainty).

1 finding from 1 review

All‐cause death · solid organ transplant recipients

Extended showed no clear difference in all‐cause death compared with short‐duration valganciclovir (low certainty).

1 finding from 1 review

All‐cause death · solid organ transplant recipients

Antiviral prophylaxis leads to lower all‐cause death compared with placebo or no treatment (high certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 0.63 [0.43, 0.92]
17 studies · 1838 participants
High

All‐cause death · solid organ transplant recipients

Low showed no clear difference in all‐cause death compared with standard dose valganciclovir (low certainty).

1 finding from 1 review

All‐cause death · solid organ transplant recipients

Maribavir showed no clear difference in all‐cause death compared with ganciclovir (low certainty).

1 finding from 1 review