Findings

What do systematic reviews say?

10 questions · 11 findings · 3 reviews · Developmental, Psychosocial and Learning Problems

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No studies found 7 · 63.6%GRADE not reported 0 · 0%Very low 2 · 18.2%Low 1 · 9.1%Moderate 1 · 9.1%High 0 · 0%

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological intervention for irritability, aggression, and self‐injury in autism spectrum disorder (ASD) 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs placebo

Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological intervention for irritability, aggression, and self‐injury in autism spectrum disorder (ASD) 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Atypical antipsychotics vs placebo

Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

1 finding from 1 review

Pharmacological intervention for irritability, aggression, and self‐injury in autism spectrum disorder (ASD) 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Very low

Neurohormones vs placebo

Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological intervention for irritability, aggression, and self‐injury in autism spectrum disorder (ASD) 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nortriptyline (antidepressant) vs placebo

Aggression · men with alcohol dependency

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bromocriptine vs placebo

Aggression · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Aggression · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desipramine (antidepressant) vs placebo

Aggression · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

RISPERIDONE vs placebo

Aggression · Disruptive behaviours in children and youths

2 findings from 1 review

Atypical antipsychotics for disruptive behaviour disorders in children and youths 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 238 participants
Low
Atypical antipsychotics for disruptive behaviour disorders in children and youths 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 190 participants
Moderate

Phenytoin (antiepileptic) vs placebo

Aggression · adults with antisocial personality disorder

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low