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Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Dopamine agonist vs placebo

Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence

Any dopamine agonist showed no clear difference in adverse events as N of participants with at least one adverse event compared with placebo (moderate certainty).

1 finding from 1 review

Amantidine vs antidepressants

Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence

Amantidine showed no clear difference in adverse events as N of participants with at least one adverse event compared with antidepressants (low certainty).

1 finding from 1 review

Amantadine vs placebo

Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence

Amantadine showed no clear difference in adverse events as N of participants with at least one adverse event compared with placebo (moderate certainty).

1 finding from 1 review