Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Emergency and Critical Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

HFNC vs NIPPV or NIV

Adverse events ‐ pneumonia · adults in the ICU, requiring respiratory support

It is very uncertain whether HFNC changes adverse events Respiratory infection (pneumonia) compared with NIPPV or NIV (very low certainty).

1 finding from 1 review

High‐flow nasal cannulae for respiratory support in adult intensive care patients 2021 · Cochrane Headline outcomes only
RR 0.51 [0.17, 1.52]
3 studies · 1750 participants
Very low

HFNC vs standard oxygen therapy

Adverse events Respiratory infection (pneumonia) Nasal mucosa or skin trauma · adults in the ICU, requiring respiratory support

HFNC showed no clear difference in adverse events Respiratory infection (pneumonia) Nasal mucosa or… compared with standard oxygen therapy (moderate certainty).

1 finding from 1 review

High‐flow nasal cannulae for respiratory support in adult intensive care patients 2021 · Cochrane Headline outcomes only
RR 0.72 [0.48, 1.09]
4 studies · 1057 participants
Moderate