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Evidence found and GRADE certainty

4 questions · 4 findings · 3 reviews · Musculoskeletal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 75%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Any cold therapy vs no cold therapy following total knee replacement

Adverse events Adverse events included discomfort, local skin reactions, superficial infections, cold induced injuries and thrombolytic events · people undergoing total knee replacement

It is very uncertain whether any cold therapy changes total adverse eventsAdverse events included discomfort, local skin… compared with no cold therapy following total knee replacement (very low certainty).

1 finding from 1 review

Preoperative education vs usual care

Total number of serious adverse events (infection, thrombosis, other serious adverse events · patients with knee replacement surgery

Preoperative education showed no clear difference in total number of serious adverse events (infection, thrombosis, other… compared with usual care (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events (total): · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments

It is very uncertain whether the intervention changes adverse events (total): (very low certainty).

1 finding from 1 review

Preoperative education vs usual care

Total number of serious adverse events (infection, thrombosis, other serious adverse events · hip replacement

It is very uncertain whether preoperative education changes total number of serious adverse events (infection, thrombosis, other… compared with usual care (very low certainty).

1 finding from 1 review