Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews

No studies found 2 · 25%GRADE not reported 0 · 0%Very low 3 · 37.5%Low 2 · 25%Moderate 1 · 12.5%High 0 · 0%

Plasma‐derived C1 esterase inhibitor vs placebo or active control

Serious adverse events (during · children or adults with Types I or II HAE

It is very uncertain whether plasma‐derived C1 esterase inhibitor changes serious adverse events (during compared with placebo or active control (very low certainty).

1 finding from 1 review

Recombinant human C1 esterase inhibitor vs placebo or active control

Serious adverse events (during · children or adults with Types I or II HAE

It is very uncertain whether recombinant human C1 esterase inhibitor changes serious adverse events (during compared with placebo or active control (very low certainty).

1 finding from 1 review