Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,041 questions · 1,056 findings · 283 reviews

No studies found 346 · 32.8%GRADE not reported 111 · 10.5%Very low 326 · 30.9%Low 195 · 18.5%Moderate 66 · 6.3%High 12 · 1.1%

Rituximab/cyclosporin/prednisolone vs cyclosporin/prednisolone

Adverse events: hypotension · idiopathic steroid‐resistant nephrotic syndrome in children

It is very uncertain whether rituximab/cyclosporin/prednisolone changes adverse events: hypotension compared with cyclosporin/prednisolone (very low certainty).

1 finding from 1 review

Rituximab/cyclosporin/prednisolone vs cyclosporin/prednisolone

Adverse effects of antibiotics (skin rash) · idiopathic steroid‐resistant nephrotic syndrome in children

It is very uncertain whether rituximab/cyclosporin/prednisolone changes adverse events: skin rash compared with cyclosporin/prednisolone (very low certainty).

1 finding from 1 review

Oral retinoids: alitretinoin 10 mg vs placebo

Primary outcome 3: Adverse events · people with moderate to severe chronic hand eczema

Oral retinoids: alitretinoin 10 mg showed no clear difference in primary: all adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Corticosteroid creams/ointments: mometasone furoate cream 3 times/week vs 2 times/week

Primary outcome 3: Adverse events · people (all patch‐tested) with hand eczema > 6 months that had cleared upon daily treatment for a maximum of 9 weeks with mometasone…

Corticosteroid creams/ointments: mometasone furoate cream 3 times/week showed no clear difference in primary: adverse events compared with 2 times/week (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events · adults (age 18 years or over) with myocardial infarction, stable angina, following coronary artery bypass graft surgery or percutaneous…

The review found no eligible studies for this question.

1 finding from 1 review

Repeat midurethral tape (any type) vs any other non‐tape surgical treatment (e.g. traditional sling, colposuspension, injectables)

Adverse events · women with recurrent stress urinary incontinence after failed minimally invasive midurethral tape surgery

The review found no eligible studies for this question.

1 finding from 1 review