Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

61 questions · 61 findings · 23 reviews · Common Mental Disorders

No studies found 14 · 23%GRADE not reported 5 · 8.2%Very low 17 · 27.9%Low 16 · 26.2%Moderate 9 · 14.8%High 0 · 0%

Abrupt discontinuation vs continuation of long‐term antidepressants

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether abrupt discontinuation changes adverse events compared with continuation of long‐term antidepressants (very low certainty).

1 finding from 1 review

Tricyclic antidepressants vs placebo

Adverse events (at 4, 6 or 12 weeks) · adults with insomnia

Tricyclic antidepressants showed no clear difference in adverse events (at 4, 6 or 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Discontinuation by "tapering" vs usual family planning care

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes adverse events compared with continuation (or usual care) (very low certainty).

1 finding from 1 review

Acupuncture vs control acupuncture

Adverse events · clinical diagnosis of depression

Acupuncture showed no clear difference in adverse events compared with control acupuncture (moderate certainty).

1 finding from 1 review