Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Gut

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Any‐treatment‐dose vitamin D (greater than 400 IU/day) vs supplemental‐dose vitamin D (less than 400 IU/day)

Withdrawals due to adverse events · people with inflammatory bowel disease

It is very uncertain whether any‐treatment‐dose vitamin D (greater than 400 IU/day) changes withdrawals due to adverse events compared with supplemental‐dose vitamin D (less than 400 IU/day) (very low certainty).

1 finding from 1 review

Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
RR 3.09 [0.13, 73.17]
4 studies · 233 participants
Very low

High‐treatment‐dose vitamin D (greater than 1000 IU/day) vs low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day)

Withdrawals due to adverse events · people with inflammatory bowel disease

It is very uncertain whether high‐treatment‐dose vitamin D (greater than 1000 IU/day) changes withdrawals due to adverse events compared with low‐treatment‐dose vitamin D (400 IU/day to 1000 IU/day) (very low certainty).

1 finding from 1 review

Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
RR 0.89 [0.06, 13.08]
3 studies · 104 participants
Very low

Vitamin D vs placebo/no treatment

Withdrawals due to adverse events · people with inflammatory bowel disease

It is very uncertain whether vitamin D (all doses) changes withdrawals due to adverse events compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Vitamin D for the treatment of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
RR 1.97 [0.18, 21.27]
12 studies · 1251 participants
Very low