Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Heart

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No studies found 1 · 50%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Glycopeptide (vancomycin or teicoplanin) plus aminoglycoside (gentamicin) vs beta‐lactam (cloxacillin) plus aminoglycoside (gentamicin)

Adverse events · people with endocarditis due to Staphylococcus aureus in drug abusers

It is very uncertain whether glycopeptide (vancomycin or teicoplanin) plus aminoglycoside… changes adverse events compared with beta‐lactam (cloxacillin) plus aminoglycoside (gentamicin) (very low certainty).

1 finding from 1 review

A comparison of different antibiotic regimens for the treatment of infective endocarditis 2020 · Cochrane Headline outcomes only
RR 5.5 [0.33, 91.44]
1 study · 34 participants
Very low

Lipopeptide antibiotic (daptomycin) vs aminoglycoside (low‐dose gentamicin) plus anti‐staphylococcal penicillin (nafcillin, oxacillin or flucloxacillin) or glycopeptide antibiotic (vancomycin)

Adverse events1 · people with endocarditis caused by Staphylococcus aureus

The review found no eligible studies for this question.

1 finding from 1 review

A comparison of different antibiotic regimens for the treatment of infective endocarditis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found