Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Dementia and Cognitive Improvement

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 1 · 50%

Specific adverse events: haemorrhage · cognitively healthy people in late life

Aspirin leads to higher adverse events (haemorrhage) compared with placebo (high certainty).

1 finding from 1 review

Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia 2020 · Cochrane Headline outcomes only
RR 1.37 [1.17, 1.6]
1 study · 19114 participants
High

Gastrointestinal adverse events · older people with age‐related memory loss

NSAIDs (celecoxib) may leads to higher adverse events – gastrointestinal compared with placebo (low certainty).

1 finding from 1 review

Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia 2020 · Cochrane Headline outcomes only
RR 2.66 [1.05, 6.75]
1 study · 40 participants
Low