Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 2 reviews · Common Mental Disorders

No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 1 · 50%

Lithium vs OLANZAPINE

Adverse events · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Valproate vs OLANZAPINE

Adverse effects: 1. Sedation · Adults (aged 18 and over) with acute mania

Valproate leads to lower adverse events ‐ Sedation At 3‐12 weeks (secondary tolerability… compared with olanzapine (high certainty).

1 finding from 1 review