Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 9 findings · 6 reviews · Musculoskeletal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 55.6%Low 3 · 33.3%Moderate 1 · 11.1%High 0 · 0%

Any cold therapy vs no cold therapy following total knee replacement

Adverse events Adverse events included discomfort, local skin reactions, superficial infections, cold induced injuries and thrombolytic events · people undergoing total knee replacement

It is very uncertain whether any cold therapy changes total adverse eventsAdverse events included discomfort, local skin… compared with no cold therapy following total knee replacement (very low certainty).

1 finding from 1 review

Preoperative education vs usual care

Total number of serious adverse events (infection, thrombosis, other serious adverse events · patients with knee replacement surgery

Preoperative education showed no clear difference in total number of serious adverse events (infection, thrombosis, other… compared with usual care (low certainty).

1 finding from 1 review

Preoperative education vs usual care

Total number of serious adverse events (infection, thrombosis, other serious adverse events · hip replacement

It is very uncertain whether preoperative education changes total number of serious adverse events (infection, thrombosis, other… compared with usual care (very low certainty).

1 finding from 1 review

Trapeziectomy with interpositional arthroplasty (T and IA) vs trapeziometacarpal joint replacement (Swanson)

Adverse events Complications reported · Patients with thumb (trapeziometacarpal joint) osteoarthritis

Trapeziectomy with interpositional arthroplasty (T and IA) showed no clear difference in adverse events Complications reported compared with trapeziometacarpal joint replacement (Swanson) (low certainty).

1 finding from 1 review

Primary comparison for continuous passive motion (CPM) vs no CPM

Adverse events (a count of reported harms or adverse events/experiences over life of study/ · hospitalised patients who have undergone knee replacement surgery

Primary comparison for continuous passive motion (CPM) showed no clear difference in adverse events Counts of adverse events compared with no CPM (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events (total): · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments

It is very uncertain whether the intervention changes adverse events (total): (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events (serious ‐ resulting in hospitalisation or death) · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
1 finding from 1 review