Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

14 questions · 15 findings · 7 reviews · Oral medicine and oral cancer

No studies found 1 · 6.7%GRADE not reported 11 · 73.3%Very low 3 · 20%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Surgery plus radiotherapy vs Radiotherapy alone

Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Adverse events · All patients with cancer who are receiving treatment
2 findings from 1 review

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review

Acupuncture vs sham

Adverse events · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
1 finding from 1 review

Amifostine vs no treatment/placebo

Adverse effects (other reported events) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review

Pilocarpine vs no treatment/placebo

Adverse effects (other reported events) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review

Surgery vs Radiotherapy alone

Adverse events associated with treatment · Adults with oropharyngeal cancer
1 finding from 1 review

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs placebo or no treatment

Toxicity (adverse events probably due to drug) · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole,… showed no clear difference in toxicity (adverse events probably due to drug) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs Antifungal drugs not absorbed from GI tract

Toxicity (adverse events probably due to drug) · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract showed no clear difference in toxicity (adverse events probably due to drug) compared with antifungal drugs not absorbed from GI tract; GRADE not reported.

1 finding from 1 review