Findings

What do systematic reviews say?

5 questions · 5 findings · 4 reviews · Dental caries

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No studies found 2 · 40%GRADE not reported 2 · 40%Very low 1 · 20%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Flowable resin composite vs Fluoride-releasing resin-based sealant

Adverse events · Children who were regular dental attenders with caries-free first or second primary molars (public health service clinic, Brazil)

The review found no eligible studies for this question.

1 finding from 1 review

Sealants for preventing dental caries in primary teeth 2022 · Cochrane All outcomes
No studies reported this outcome.
0 studies
No studies found

Dental cavity liner (e.g. calcium hydroxide, glass ionomer, resin-modified glass ionomer, or flowable composite) placed under the restoration vs No liner (resin-based composite bonded directly to the tooth)

Adverse events · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth

The review found no eligible studies for this question.

1 finding from 1 review

Dental cavity liners for Class I and Class II resin‐based composite restorations 2019 · Cochrane All outcomes
None reported. No adverse events were reported in any of the included studies (0 studies contributed adverse-events data).
0 studies
No studies found

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Adverse events: 22 surgical complications in the PET-CT group vs 83 in the planned-surgery group (Mehanna 2017).
1 study · 564 participants
Very low

Chlorhexidine gel (0.12%) vs no treatment

Adverse events · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
24 months · primary dentition
Both studies reported there were no adverse events.
2 studies
GRADE not reported

Chlorhexidine varnish vs placebo or no treatment

Adverse events (e.g. ulcers, tooth staining) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
One study reported no adverse events for ulcers or tooth staining. One study stated "side-effects due to the CHX treatment were not noted".
2 studies
GRADE not reported