Findings

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8 questions · 8 findings · 2 reviews · Orthodontics

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No studies found 4 · 50%GRADE not reported 3 · 37.5%Very low 1 · 12.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Psychological interventions vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)

1 finding from 1 review

Interventions for the cessation of non‐nutritive sucking habits in children 2015 · Cochrane All outcomes
SoF (psychological interventions vs no treatment): Adverse events - insufficient information reported. Table 3 (adverse outcomes after one month; Haryett 1967), psychological treatment group: reported upset 1/11 (9%);…
1 study
GRADE not reported

Ibuprofen taken pre-emptively (about 1 hour before treatment) vs Ibuprofen taken post-treatment

Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
No studies in this comparison reported any adverse events.
0 studies
No studies found

NSAID (systemic) vs paracetamol

Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
In one study, one participant (<1%) in the paracetamol group experienced drug hypersensitivity (a 'red, blotchy and itchy rash') that resolved without treatment within 1 week (Bradley 2007 / McAlinden 2005); 1 RCT;…
1 study
Very low

Topical NSAID (ketoprofen lysinate mouthwash, 160 mg) vs Topical NSAID (benzidamine hydrochloride mouthwash, 22.5 mg)

Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
The study did not report this outcome.
0 studies
No studies found

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
No studies in this comparison reported any adverse events. SoF cell: 'Not reported'.
0 studies
No studies found

Topical NSAID (ketoprofen chewing gum) vs Local anaesthetic (benzocaine chewing gum)

Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
The study did not report this outcome.
0 studies
No studies found

Orthodontic appliances (palatal crib) vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)

1 finding from 1 review

Interventions for the cessation of non‐nutritive sucking habits in children 2015 · Cochrane All outcomes
SoF (orthodontic appliances vs no treatment): Adverse events - insufficient information reported. Table 3 (adverse outcomes after one month; Haryett 1967), orthodontic treatment group: reported upset 6/22 (27%); speech…
1 study
GRADE not reported

Psychological intervention + orthodontic treatment (palatal crib or palatal arch) vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)

1 finding from 1 review

Interventions for the cessation of non‐nutritive sucking habits in children 2015 · Cochrane All outcomes
Table 3 (adverse outcomes after one month; Haryett 1967), combined psychological plus orthodontic treatment group: reported upset 4/22 (18%); speech difficulty 6/22 (27%); eating difficulty 6/22 (27%); developing…
1 study
GRADE not reported