Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 13 reviews · Metabolic and Endocrine Disorders

No studies found 9 · 36%GRADE not reported 1 · 4%Very low 10 · 40%Low 5 · 20%Moderate 0 · 0%High 0 · 0%

Intervention not reported

Adverse events 1. All adverse events 2. Drop‐outs due to adverse events Interventions vs thiazolidinediones [1. 6 months to 12 months] [2. 24 weeks to 52 weeks] · participants with type 2 diabetes mellitus

The intervention may leads to lower adverse events 1. All adverse events 2. Drop‐outs due to adverse… (low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review