Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Musculoskeletal

No studies found 0 · 0%GRADE not reported 4 · 66.7%Very low 0 · 0%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%

Total adverse events · acute gout

High‐dose may leads to higher total adverse events compared with low‐dose colchicine (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 2.11 [1.51, 2.95]
1 study · 126 participants
Low

Serious adverse events · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 126 participants
GRADE not reported

Withdrawals due to adverse events · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 126 participants
GRADE not reported

Total adverse events · acute gout

High‐dose colchicine may leads to higher total adverse events compared with placebo (low certainty).

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
RR 3.21 [2.01, 5.11]
2 studies · 124 participants
Low

Serious adverse events · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 111 participants
GRADE not reported

Withdrawals due to adverse events · acute gout

1 finding from 1 review

Colchicine for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 111 participants
GRADE not reported