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Evidence found and GRADE certainty

4 questions · 4 findings · 2 reviews · Sexually Transmitted Infections

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Doxycycline vs quinolones

Adverse events (Analysis 1.7) Participant's report · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

It is very uncertain whether doxycycline changes adverse events Men and women Assessed by participants' self‐report compared with quinolones (very low certainty).

1 finding from 1 review

Azithromycin vs doxycycline

Adverse events Men · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

Azithromycin showed no clear difference in adverse events Men compared with doxycycline (low certainty).

1 finding from 1 review

Azithromycin vs doxycycline

Adverse events Men and women · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

Azithromycin probably leads to lower adverse events Men and women compared with doxycycline (moderate certainty).

1 finding from 1 review

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID

Regimens containing macrolides (azithromycin) showed no clear difference in adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing tetracycline (doxycycline) (low certainty).

1 finding from 1 review