Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

458 questions · 473 findings · 205 reviews

No studies found 128 · 27.1%GRADE not reported 49 · 10.4%Very low 142 · 30%Low 106 · 22.4%Moderate 36 · 7.6%High 12 · 2.5%

Comparison 2: any simplified antibiotic regimen vs 7 days injectable benzylpenicillin + injectable gentamicin

Adverse events · neonates with possible serious bacterial infection

Comparison 2: any simplified antibiotic regimen showed no clear difference in adverse events compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).

1 finding from 1 review

Comparison 2: 7 days oral amoxicillin + injectable gentamicin vs 7 days injectable benzylpenicillin + injectable gentamicin

Adverse events · neonates with possible serious bacterial infection

Comparison 2: 7 days oral amoxicillin + injectable gentamicin showed no clear difference in adverse events compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).

1 finding from 1 review

PDEI + 5‐ARI vs 5‐ARI alone

Adverse events

The review found no eligible studies for this question.

2 findings from 1 review