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What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews · Anaesthesia

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

NSAIDs vs control or placebo medications

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

Nonsteroidal anti‐inflammatory drugs (NSAIDs) showed no clear difference in adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo medications (low certainty).

1 finding from 1 review

Dexmedetomidine vs control or placebo medications

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

Dexmedetomidine showed no clear difference in adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo medications (low certainty).

1 finding from 1 review

Pregabalin or Gabapentin vs control or placebo medications

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

Pregabalin or Gabapentin may leads to lower adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo medications (low certainty).

1 finding from 1 review

Scalp infiltration vs placebo or control

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

Scalp infiltration showed no clear difference in adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo intervention (low certainty).

1 finding from 1 review

Scalp block vs placebo or control

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

It is very uncertain whether scalp block changes adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo intervention (very low certainty).

1 finding from 1 review