Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 2 · 40%GRADE not reported 0 · 0%Very low 3 · 60%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Postnatal prophylaxis: LMWH vs no treatment/placebo

Adverse effects sufficient to stop treatment · women at increased risk of VTE in the early postpartum period

The review found no eligible studies for this question.

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LMWH prophylaxis vs UFH

Adverse effects sufficient to stop treatment · pregnant women at increased risk of VTE during pregnancy and the early postnatal period

It is very uncertain whether antenatal (± postnatal) prophylaxis: LMWH changes adverse effects sufficient to stop treatment compared with UFH (very low certainty).

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
RR 0.07 [0.01, 0.54]
2 studies · 226 participants
Very low

Peripartum/postnatal prophylaxis (caesarean): LMWH vs UFH

Adverse effects sufficient to stop treatment · women giving birth by elective or emergency caesarean (elective or emergency (1 trial), elective cesarean only (1 trial),…

The review found no eligible studies for this question.

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Heparin prophylaxis vs no treatment/placebo

Adverse effects sufficient to stop treatment · pregnant women at increased risk of VTE during pregnancy and the early postnatal period

It is very uncertain whether antenatal (± postnatal) prophylaxis: heparin (LMWH or UFH) changes adverse effects sufficient to stop treatment compared with no treatment/placebo (very low certainty).

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
RR 0.49 [0.05, 5.31]
1 study · 139 participants
Very low

Peripartum/postnatal prophylaxis (caesarean): heparin (LMWH or UFH) vs no treatment/placebo

Adverse effects sufficient to stop treatment · women giving birth by elective or emergency caesarean (elective only (1 trial), emergency or elective (4 trials))

1 finding from 1 review

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 140 participants
Very low