Intranasal beta‐estradiol vs placebo
Adverse effects Intranasal beta‐estradiol 0.021 mg/day, 0.029 mg/day or 0.040 mg/day · women with hot flushes
Intranasal beta‐estradiol probably leads to higher adverse effects Intranasal beta‐estradiol 0.021 mg/day, 0.029 mg/day… compared with placebo (moderate certainty).
1 finding from 1 review
- OR 1.96 [1.26, 3.03]1 study · 458 participantsModerate