Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics
Adverse effects · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)
1 finding from 1 review
- Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes3 days1 participant reported diarrhoea (placebo group); 1 participant reported fatigue and reduced energy postoperatively (antibiotic group). 61 participants (2 studies).2 studies · 61 participantsVery low