What do systematic reviews say?

QUETIAPINE vs CLOZAPINE ‐ all data short term

QUETIAPINE probably leads to lower adverse effects: 1. Sedation compared with CLOZAPINE ‐ all data short term (moderate certainty).

• Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
  RR 0.22 [0.11, 0.47]
  2 studies · 135 participants
  Moderate

QUETIAPINE vs OLANZAPINE

QUETIAPINE showed no clear difference in adverse effects: 1. Sedation compared with OLANZAPINE (moderate certainty).

• Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
  RR 0.98 [0.84, 1.13]
  7 studies · 1615 participants
  Moderate

QUETIAPINE vs PALIPERIDONE

• Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

QUETIAPINE vs RISPERIDONE

QUETIAPINE led to higher adverse effects: 1. Sedation compared with RISPERIDONE; GRADE not reported.

• Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
  RR 1.21 [1.06, 1.38]
  8 studies · 2226 participants
  GRADE not reported

QUETIAPINE vs ZIPRASIDONE

QUETIAPINE may leads to higher adverse effects: 1. Sedation compared with ZIPRASIDONE (low certainty).

• Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
  RR 1.36 [1.03, 1.81]
  2 studies · 754 participants
  Low

QUETIAPINE vs ARIPIPRAZOLE

• Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported