Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Heart

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Monoclonal antibody vs polyclonal antibody

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

Monoclonal antibody showed no clear difference in acute rejection Acute rejection grade 3A or more verified by biopsy compared with polyclonal antibody (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 0.96 [0.67, 1.37]
3 studies · 146 participants
Low

Interleukin‐2 RA induction vs monoclonal antibody induction

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

Interleukin‐2 RA induction showed no clear difference in acute rejection Acute rejection grade 3A or more verified by biopsy compared with monoclonal antibody induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 0.97 [0.77, 1.23]
2 studies · 159 participants
Low