Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 2 · 40%Moderate 1 · 20%High 1 · 20%

Acute rejection · solid organ transplant recipients

Ganciclovir showed no clear difference in acute rejection compared with aciclovir (high certainty).

1 finding from 1 review

Acute rejection · solid organ transplant recipients

It is very uncertain whether valaciclovir changes acute rejection compared with ganciclovir or valganciclovir (very low certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 0.91 [0.22, 3.73]
3 studies · 271 participants
Very low

Acute rejection · solid organ transplant recipients

Extended probably leads to lower acute rejection compared with short‐duration valganciclovir (moderate certainty).

1 finding from 1 review

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients 2024 · Cochrane Headline outcomes only
RR 0.64 [0.43, 0.95]
2 studies · 454 participants
Moderate

Acute rejection · solid organ transplant recipients

Low showed no clear difference in acute rejection compared with standard dose valganciclovir (low certainty).

1 finding from 1 review

Acute rejection · solid organ transplant recipients

Maribavir showed no clear difference in acute rejection compared with ganciclovir (low certainty).

1 finding from 1 review