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What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 5 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 1 · 20%High 0 · 0%

Dopamine agonist vs placebo

Point abstinence (number of participants who were abstinent at the end of the treatment) · patients with the treatment of cocaine dependence

Any dopamine agonist showed no clear difference in abstinence (objective) Participants abstinent at the end of… compared with placebo (low certainty).

1 finding from 1 review

Amantadine vs placebo

Abstinence · patients with the treatment of cocaine dependence

Amantadine showed no clear difference in abstinence (objective) N of subjects abstinent at the end of the study compared with placebo (low certainty).

2 findings from 1 review