Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Amantidine vs antidepressants

Abstinence · patients with the treatment of cocaine dependence

Amantidine may leads to lower abstinence (objective) N of subjects abstinent at the end of the study compared with antidepressants (low certainty).

1 finding from 1 review

Dopamine agonists for the treatment of cocaine dependence 2015 · Cochrane Headline outcomes only
RR 0.25 [0.12, 0.53]
2 studies · 68 participants
Low

Amantadine vs placebo

Abstinence · patients with the treatment of cocaine dependence

Amantadine showed no clear difference in abstinence (objective) N of subjects abstinent at the end of the study compared with placebo (low certainty).

1 finding from 1 review

Dopamine agonists for the treatment of cocaine dependence 2015 · Cochrane Headline outcomes only
RR 1.13 [0.59, 2.13]
5 studies · 275 participants
Low