Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

50% or greater reduction in seizure frequency · people with drug‐resistant focal epilepsy

Rufinamide probably leads to higher 50% or greater reduction in seizure frequency ‐ ITT analysis compared with placebo (moderate certainty).

1 finding from 1 review

Rufinamide add‐on therapy for drug‐resistant epilepsy 2020 · Cochrane Headline outcomes only
RR 1.79 [1.44, 2.22]
6 studies · 1759 participants
Moderate