Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 4 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

nCaF2 primer vs Control Transbond primer

Enamel demineralization (DIAGNOdent score) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

nCaF2 primer favored lower demineralization scores, but certainty was not graded.

1 finding from 1 review

Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed Orthodontic… 2024 All outcomes
1, 3, and 6 months after bonding · Fixed orthodontic treatment
Statistically significant scores in favor of the nCaF2 primer at T1, T3, and T6 (p-value = 0.000).
1 study · 31 participants
GRADE not reported

nCaF2 primer vs Control Transbond primer

Photographic white spot lesion score · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

nCaF2 primer showed no clinical photographic WSL difference at debonding, with certainty not graded.

1 finding from 1 review

Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed Orthodontic… 2024 All outcomes
Before and after treatment · Fixed orthodontic treatment
No significant differences in the WSLs photographic scores of the control group with the contralateral nCaF2 group before and after bonding.
1 study · 31 participants
GRADE not reported

nCaF2 primer vs Control Transbond primer

Streptococcus mutans count · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

nCaF2 primer differed in S. mutans count only at T1, with certainty not graded.

1 finding from 1 review

Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed Orthodontic… 2024 All outcomes
1, 3, and 6 months after bonding · Fixed orthodontic treatment
Statistically significant difference in bacterial count between the two primers only at T1 (p-value = 0.000).
1 study · 31 participants
GRADE not reported

nCaF2 primer vs Control Transbond primer

White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)

A single small split-mouth RCT found the nCaF2-containing primer reduced demineralization (DIAGNOdent) but showed no significant clinical white spot lesion difference at debonding (ungraded).

1 finding from 1 review

Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed Orthodontic… 2024 All outcomes
1, 3 and 6 months (during treatment to debonding) · Orthodontic clinical practice (in-vivo human clinical trials); adolescents and adults
Al Tuma 2023 (1 split-mouth RCT, 31 patients / 310 teeth): DIAGNOdent scores significantly favored the nCaF2 primer at 1, 3 and 6 months (p=0.000) and S. mutans count differed at 1 month; no significant difference in…
1 study · 31 participants
GRADE not reported