Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

Vitamin E vs placebo

Progression to late AMD (neovascular AMD, geographic atrophy or both) · people with AMD

It is very uncertain whether vitamin E changes progression to late AMD (neovascular AMD, geographic atrophy or both) compared with placebo (very low certainty).

1 finding from 1 review

Antioxidant vitamin and mineral supplements for slowing the progression of age‐related macular degeneration 2023 · Cochrane Headline outcomes only
RR 1.36 [0.31, 6.05]
1 study · 998 participants
Very low

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to late AMD (neovascular AMD, geographic atrophy or both) · people with AMD

Antioxidant multivitamin and mineral supplement probably leads to lower progression to late AMD (neovascular AMD, geographic atrophy, or both) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antioxidant vitamin and mineral supplements for slowing the progression of age‐related macular degeneration 2023 · Cochrane Headline outcomes only
OR 0.72 [0.58, 0.9]
3 studies · 2445 participants
Moderate