Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Oral medicine and oral cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Vital staining (e.g. toluidine blue, tolonium chloride) vs Surgical or punch biopsy with histological assessment

Specificity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions

1 finding from 1 review

Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident… 2021 · Cochrane All outcomes
Specificity 0.68 [0.58, 0.77]
20 studies
Very low

Vital staining (e.g. toluidine blue, tolonium chloride) vs Surgical or punch biopsy with histological assessment

Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions

1 finding from 1 review

Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident… 2021 · Cochrane All outcomes
Sensitivity 0.86 [0.79, 0.90]
20 studies
Low