What do systematic reviews say?

9 questions · 9 findings · 4 reviews · Oral Health

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No studies found 1 · 11.1%GRADE not reported 2 · 22.2%Very low 4 · 44.4%Low 2 · 22.2%Moderate 0 · 0%High 0 · 0%

Visual examination (VE) vs Reference standard: histology

Sensitivity · Extracted molar teeth of adults with resin composite approximal restorations (in vitro; secondary root caries; Switzerland)

1 finding from 1 review

Tests to detect and inform the diagnosis of root caries 2020 · Cochrane All outcomes
Sensitivity 0.75 [0.48, 0.93]
1 study
Very low

Visual examination (VE) vs Reference standard: histology

Specificity · Extracted molar teeth of adults with resin composite approximal restorations (in vitro; secondary root caries; Switzerland)

1 finding from 1 review

Tests to detect and inform the diagnosis of root caries 2020 · Cochrane All outcomes
Specificity 0.38 [0.14, 0.68]
1 study
Very low

Radiograph and visual examination in combination vs Reference standard: histology

Specificity · Extracted molar teeth of adults with resin composite approximal restorations (in vitro; secondary root caries; Switzerland)

1 finding from 1 review

Tests to detect and inform the diagnosis of root caries 2020 · Cochrane All outcomes
Specificity 0.54 [0.25, 0.81]
1 study
Very low

Radiograph and visual examination in combination vs Reference standard: histology

Sensitivity · Extracted molar teeth of adults with resin composite approximal restorations (in vitro; secondary root caries; Switzerland)

1 finding from 1 review

Tests to detect and inform the diagnosis of root caries 2020 · Cochrane All outcomes
Sensitivity 0.81 [0.54, 0.96]
1 study
Very low

Visual examination (VE) vs Reference standard: examination and clinical evaluation by a physician/clinician with specialist knowledge or training (long-term follow-up accepted for those screened negative)

Specificity for detection of oral cavity cancer/OPMD · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…

1 finding from 1 review

Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy… 2021 · Cochrane All outcomes
Summary of findings 1 (no pooled analysis): for the 7 low-prevalence studies specificity ranged from 0.94 (95% CI 0.88 to 0.97) to 0.99 (95% CI 0.98 to 1.00); for the 3 higher-prevalence studies specificity ranged from…
10 studies · 25568 participants
Low

Visual examination (VE) vs Reference standard: examination and clinical evaluation by a physician/clinician with specialist knowledge or training (long-term follow-up accepted for those screened negative)

Sensitivity for detection of oral cavity cancer/OPMD · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…

1 finding from 1 review

Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy… 2021 · Cochrane All outcomes
Summary of findings 1 (no pooled analysis): for the 7 studies with low prevalence (<=10%) sensitivity ranged from 0.50 (95% CI 0.07 to 0.93) to 0.99 (95% CI 0.97 to 1.00); for the 3 higher-prevalence studies…
10 studies · 25568 participants
Low

Combined index test: visual examination + radiograph + DIAGNOdent (Alomari 2015) vs Reference standard: histology

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

1 finding from 1 review

Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies)
Sensitivity 0.82 [0.75, 0.88]
1 study
GRADE not reported

Combined index test: visual examination + radiograph + DIAGNOdent (Alomari 2015) vs Reference standard: histology

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

1 finding from 1 review

Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies)
Specificity 0.65 [0.38, 0.86]
1 study
GRADE not reported

Transillumination/OCT device used as an adjunct to a conventional visual examination vs Reference standard: histology, or enhanced visual examination with or without radiographs (also operative excavation, tooth separation, or microcomputed tomography)

Outcome not reported · Children or adults presenting asymptomatically or suspected of having enamel caries (clinical/in vivo studies); extracted teeth of…

The review found no eligible studies for this question.

1 finding from 1 review

Transillumination and optical coherence tomography for the detection and diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)
No studies formally reported the use of the illumination devices as an adjunct to a conventional visual examination, and therefore it has not been possible to make an assessment.
0 studies
No studies found