Valproate vs placebo
Valproate showed no clear difference in dropout rate ‐ All‐cause 3‐8 weeks (secondary acceptability outcome) compared with placebo (moderate certainty).
- OR 0.83 [0.64, 1.07]6 studies · 1156 participantsModerate
Valproate showed no clear difference in dropout rate ‐ All‐cause 3‐8 weeks (secondary acceptability outcome) compared with placebo (moderate certainty).
It is very uncertain whether valproate changes dropout rate ‐ All‐cause At 8 weeks (secondary acceptability outcome) compared with lithium (very low certainty).
Valproate showed no clear difference in dropout rate ‐ All‐cause At 4‐6 weeks (secondary acceptability… compared with placebo (low certainty).
Valproate showed no clear difference in dropout rate ‐ All‐cause At 2‐4 weeks (secondary acceptability… compared with lithium (moderate certainty).
Valproate showed no clear difference in dropout rate ‐ All‐cause At 3‐12 weeks (secondary acceptability… compared with olanzapine (high certainty).
Valproate showed no clear difference in dropout rate ‐ All‐cause (secondary acceptability outcome) At 5 ‐ 12… compared with risperidone (low certainty).
It is very uncertain whether VALPROATE + ANTIPSYCHOTICS changes leaving the study early: Acceptability of treatment Leaving the… compared with ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone (very low certainty).