What do systematic reviews say?

Two doses of HPV vaccine vs three doses of HPV vaccine

Two doses of HPV vaccine showed no clear difference in mortality at up to 5‐year compared with three doses of HPV vaccine (low certainty).

• Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
  OR 0.33 [0.01, 8.19]
  3 studies · 1797 participants
  Low

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

• Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 481 participants
  Low