Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 25%Low 2 · 50%Moderate 1 · 25%High 0 · 0%

Twice daily or more vs once daily topical corticosteroid

Clinician‐reported signs of eczema: IGA (number with cleared or marked improvement); short term (earliest time point within 1‐4 weeks) · children and adults, most with moderate to severe eczema

Twice daily or more showed no clear difference in clinician‐reported signs of eczema: IGA (number with cleared or… compared with once daily topical corticosteroid (moderate certainty).

1 finding from 1 review

Twice daily or more vs once daily topical corticosteroid

Patient‐reported symptoms of eczema · children and adults, most with moderate to severe eczema

Twice daily or more showed no clear difference in patient‐reported symptoms of eczema: PGA (number with cleared or… compared with once daily topical corticosteroid (low certainty).

1 finding from 1 review