What do systematic reviews say?

Triple therapy vs LABA/LAMA combination

Triple therapy may leads to lower moderate‐to‐severe exacerbations (rate) compared with LABA/LAMA combination (low certainty).

• Inhaled corticosteroids with combination inhaled long‐acting beta2‐agonists and long‐acting muscarinic antagonists for… 2023 · Cochrane Headline outcomes only
  RR 0.74 [0.67, 0.81]
  4 studies · 15397 participants
  Low