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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Headline outcomes only

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No studies found 2 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 12.5%High 5 · 62.5%

Topical ivermectin vs topical metronidazole

QoL · Participants with rosacea

Topical ivermectin leads to higher HRQOL DLQI, proportion of participants that reported at end of study… compared with topical metronidazole (high certainty).

1 finding from 1 review

Topical ivermectin vs topical metronidazole

Participant‐assessed improvement in rosacea severity · Participants with rosacea

Topical ivermectin leads to higher participant‐assessed improvement in rosacea severity Likert scale ‐… compared with topical metronidazole (high certainty).

1 finding from 1 review

Topical ivermectin vs topical metronidazole

Proportion of participants with adverse event · Participants with rosacea

Topical ivermectin showed no clear difference in proportion of participants with adverse event compared with topical metronidazole (moderate certainty).

1 finding from 1 review

Topical ivermectin vs topical metronidazole

Physician‐assessed improvement in rosacea severity · Participants with rosacea

Topical ivermectin leads to higher physician‐assessed improvement in rosacea severity compared with topical metronidazole (high certainty).

1 finding from 1 review