Findings

What do systematic reviews say?

10 questions · 10 findings · 2 reviews · Oral Health

Sort:Best matchNewest Highest certainty Download CSV

No studies found 5 · 50%GRADE not reported 0 · 0%Very low 2 · 20%Low 3 · 30%Moderate 0 · 0%High 0 · 0%

Topical corticosteroids vs Another topical agent or placebo

Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Topical corticosteroids vs Another topical agent or placebo

Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Topical corticosteroids vs Another topical agent or placebo

Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Topical corticosteroids vs Another topical agent or placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Topical corticosteroids vs Another topical agent or placebo

Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Topical corticosteroids vs placebo

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical corticosteroid showed no clear difference in clinical score compared with placebo (low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
end of treatment
MD -0.38 [-0.89, 0.14]
1 study · 32 participants
Low

Topical corticosteroids vs placebo

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical corticosteroid changes clinical resolution compared with placebo (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
8-9 weeks
RR 6.00 [0.76, 47.58]
2 studies · 72 participants
Very low

Topical corticosteroids vs placebo

Adverse effects · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical corticosteroid changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
3-9 weeks
RR 1.48 [0.48, 4.56]
3 studies · 88 participants
Very low

Topical corticosteroids vs placebo

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical corticosteroid may leads to higher pain resolution compared with placebo (low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
8-9 weeks
RR 1.91 [1.08, 3.36]
2 studies · 72 participants
Low

Topical corticosteroids vs placebo

Pain (mean score, 0-10) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical corticosteroid may leads to lower pain (mean score, 0-10) compared with placebo (low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
end of treatment
MD -1.81 [-3.54, -0.09]
1 study · 32 participants
Low