Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Topical aciclovir (short‐term) vs placebo

Incidence of herpes labialis during use of the preventative intervention · participants with recurrent herpes labialis

Topical aciclovir (short‐term) showed no clear difference in incidence of herpes labialis during use of the preventative… compared with placebo (moderate certainty).

1 finding from 1 review

Topical aciclovir and 348U87 cream (short‐term) vs placebo

Incidence of herpes labialis during use of the preventative intervention · participants with recurrent herpes labialis

It is very uncertain whether topical aciclovir and 348U87 cream (short‐term) changes incidence of herpes labialis during use of the preventative… compared with placebo (very low certainty).

2 findings from 1 review