Topical NSAID (ketoprofen chewing gum) vs Local anaesthetic (benzocaine chewing gum)
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
It is very uncertain whether topical NSAID (ketoprofen chewing gum) changes pain intensity (VAS 0-100 mm) compared with local anaesthetic (benzocaine chewing gum) (very low certainty).
1 finding from 1 review
- Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes2 hoursMD 13 [-3.45, 29.45]1 study · 48 participantsVery low