What do systematic reviews say?

9 questions · 9 findings · 1 reviews · Dental public health and special care

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No studies found 3 · 33.3%GRADE not reported 1 · 11.1%Very low 2 · 22.2%Low 3 · 33.3%Moderate 0 · 0%High 0 · 0%

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

All‐cause mortality · Critically ill adults receiving mechanical ventilation in ICU

Toothbrushing (with or without antiseptics), as part of oral hygiene… showed no clear difference in mortality compared with no toothbrushing (with or without antiseptics) (low certainty).

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Follow-up: mean 1 month
RR 0.84 [0.67, 1.05]
5 studies · 910 participants
Low

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Systemic antibiotic use · Critically ill adults receiving mechanical ventilation in ICU

The review found no eligible studies for this question.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
This outcome was not reported by any of the studies in this comparison.
0 studies
No studies found

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Caregivers' preferences for oral hygiene care · Critically ill adults receiving mechanical ventilation in ICU

The review found no eligible studies for this question.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
The outcome of caregivers' preferences was not reported by any study in this comparison.
0 studies
No studies found

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Incidence of VAP · Critically ill adults receiving mechanical ventilation in ICU

Toothbrushing (with or without antiseptics), as part of oral hygiene… may leads to lower incidence of VAP compared with no toothbrushing (with or without antiseptics) (low certainty).

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Follow-up: mean 1 month
RR 0.61 [0.41, 0.91]
5 studies · 910 participants
Low

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Plaque · Critically ill adults receiving mechanical ventilation in ICU

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Plaque score: one study (Yao 2011) showed evidence of reduced plaque in the toothbrushing group; no usable pooled estimate.
1 study
GRADE not reported

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Duration of mechanical ventilation · Critically ill adults receiving mechanical ventilation in ICU

Toothbrushing (with or without antiseptics), as part of oral hygiene… showed no clear difference in duration of mechanical ventilation compared with no toothbrushing (with or without antiseptics) (low certainty).

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Follow-up: mean 1 month
MD -0.43 [-1.17, 0.30]
4 studies · 810 participants
Low

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Cost / economic data · Critically ill adults receiving mechanical ventilation in ICU

The review found no eligible studies for this question.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
The outcome of cost was not reported by any study in this comparison.
0 studies
No studies found

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Adverse effects · Critically ill adults receiving mechanical ventilation in ICU

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Adverse effects: information from two studies, which stated that there were none; very low certainty. There is a lack of evidence about adverse effects.
2 studies
Very low

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Duration of ICU stay · Critically ill adults receiving mechanical ventilation in ICU

It is very uncertain whether toothbrushing (with or without antiseptics), as part of oral hygiene… changes duration of ICU stay compared with no toothbrushing (with or without antiseptics) (very low certainty).

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Follow-up: mean 1 month
MD -1.89 [-3.52, -0.27]
3 studies · 749 participants
Very low