Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Unscheduled bleeding (all doses) · postmenopausal women with or without vasomotor symptoms

Tibolone probably leads to lower unscheduled bleeding (all doses) compared with combined HT (moderate certainty).

1 finding from 1 review

Short‐term and long‐term effects of tibolone in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 0.32 [0.24, 0.41]
16 studies · 6438 participants
Moderate

Unscheduled bleeding (all doses) · postmenopausal women with or without vasomotor symptoms

Tibolone probably leads to higher unscheduled bleeding (all doses) compared with placebo (moderate certainty).

1 finding from 1 review

Short‐term and long‐term effects of tibolone in postmenopausal women 2016 · Cochrane Headline outcomes only
OR 2.79 [2.1, 3.7]
9 studies · 7814 participants
Moderate