Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 14 findings · 2 reviews · Oral Health

No studies found 6 · 42.9%GRADE not reported 7 · 50%Very low 1 · 7.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Tetracycline + SRP vs SRP

Probing pocket depth · Adults with aggressive periodontitis

The review found no eligible studies for this question.

2 findings from 1 review

Tetracycline + SRP vs SRP

Clinical attachment level (CAL) · Adults with aggressive periodontitis

Tetracycline + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.

3 findings from 1 review

Tetracycline + SRP vs SRP

Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis

The review found no eligible studies for this question.

2 findings from 1 review

Tetracycline suspension (250 mg, held in mouth 2 minutes then swallowed, four times daily for 5 days) vs placebo

Adjusted maximum ulcer size and adjusted maximum pain · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

Tetracycline suspension (250 mg, held in mouth 2 minutes then swallowed, four times daily for 5 days) vs placebo

Average number of new lesions per week · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Tetracycline suspension (250 mg, held in mouth 2 minutes then… showed no clear difference in average number of new lesions per week compared with placebo; GRADE not reported.

1 finding from 1 review