Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

22 questions · 26 findings · 4 reviews

No studies found 8 · 30.8%GRADE not reported 3 · 11.5%Very low 2 · 7.7%Low 2 · 7.7%Moderate 11 · 42.3%High 0 · 0%

Tacrolimus 0.1% vs vehicle

Primary: adverse events ‐ burning/itching at application site · people with moderate to severe nickel sulphate‐induced allergic contact dermatitis based on clinical history (hand eczema) and proven by…

Topical calcineurin inhibitors: tacrolimus 0.1% ointment showed no clear difference in primary: adverse events ‐ burning/itching at application site compared with vehicle (moderate certainty).

1 finding from 1 review

Tacrolimus 0.1% vs vehicle

Secondary: investigator‐rated reduction in severity ‐ Not measured · people with moderate to severe nickel sulphate‐induced allergic contact dermatitis based on clinical history (hand eczema) and proven by…

The review found no eligible studies for this question.

1 finding from 1 review